Page 7 - Demo

Journal of Rural Medicine%u4e61%u6751%u533b%u5b66%u7b2c 2 %u5377%u25c6%u7b2c 4 %u671f%u25c6%u7248%u672c 1.0 %u25c6 2025 %u5e74%u6587%u7ae0%u7c7b%u578b%uff1a%u8bba%u6587 | %u520a%u53f7%uff08ISSN%uff09%uff1a3060-947X1 Copyright %u00a9 This work is licensed under a Commons Attibution-Non Commercial 4.0 International License.%u7cbe%u795e%u5206%u88c2%u75c7%u60a3%u8005%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u8303%u56f4%uff1a%u57fa%u4e8e%u6cbb%u7597%u836f%u7269%u76d1%u6d4b%u7684%u7814%u7a76%u7530 %u79d8 1%uff0c2%uff0c%u515a %u4f1f 1%uff0c2%uff0c%u9648%u5ef6%u660e 2%uff0c%u4e01 %u9756 2%uff0c%u6b27 %u76fc 2%uff081. %u897f%u5b89%u533b%u5b66%u9662%u7814%u7a76%u751f%u5904%uff0c%u9655%u897f%uff0c%u897f%u5b89%uff0c710021%uff1b2. %u897f%u5b89%u5e02%u7cbe%u795e%u536b%u751f%u4e2d%u5fc3%uff0c%u9655%u897f%uff0c%u897f%u5b89%uff0c710061%uff09DOI:10.12238/jrm.v2i4.14329%u3010%u6458%u8981%u3011%u76ee%u7684%uff1a%u5206%u6790%u63a2%u8ba8%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u7684%u4e3b%u8981%u5f71%u54cd%u56e0%u7d20%uff0c%u5236%u5b9a%u6c28%u78fa%u5fc5%u5229%u6cbb%u7597%u836f%u7269%u6d53%u5ea6%u53c2%u8003%u8303%u56f4%uff0c%u4e3a%u4e2d%u56fd%u7cbe%u795e%u5206%u88c2%u75c7%u60a3%u8005%u7fa4%u4f53%u7684%u4e2a%u4f53%u5316%u7528%u836f%u63d0%u4f9b%u53c2%u8003%u3002%u65b9%u6cd5%uff1a%u56de%u987e%u6027%u6536%u96c6%u5e76%u5206%u6790%u4e86 142 %u4f8b%u63a5%u53d7%u6c28%u78fa%u5fc5%u5229%u7247%u6cbb%u7597%u7684%u7cbe%u795e%u5206%u88c2%u75c7%u4f4f%u9662%u60a3%u8005 TDM %u7ed3%u679c%u53ca%u7528%u836f%u60c5%u51b5%u3002%u5229%u7528%u5355%u56e0%u7d20%u5206%u6790%u548c%u591a%u5143%u7ebf%u6027%u56de%u5f52%u5206%u6790%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u7684%u5f71%u54cd%u56e0%u7d20%uff1b%u6839%u636e PANSS %u91cf%u8868%u8bc4%u5206%u7ed3%u679c%u53ca%u51cf%u5206%u7387%u8bc4%u4f30%u60a3%u8005%u63a5%u53d7%u6c28%u78fa%u5fc5%u5229%u6cbb%u7597%u7684%u6709%u6548%u6027%u3002%u7ed3%u679c%uff1a%u5171%u7eb3%u5165 142 %u4f8b%u60a3%u8005%uff0c%u5176%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u7684%u4e2d%u4f4d%u6570%u4e0e%u8840%u6d46%u6d53%u5ea6 / %u5242%u91cf%u6bd4%u503c%uff08C/D%uff09%u5206%u522b%u4e3a 458.7ng/mL%u548c 8.38%u3002%u8eab%u4f53%u8d28%u91cf%u6307%u6570%uff08Body mass index, BMI%uff09%u4e0e%u6c28%u78fa%u5fc5%u5229 C/D %u503c%u5448%u663e%u8457%u8d1f%u76f8%u5173%uff08p %uff1c 0.05%uff09%uff0c%u6839%u636e BMI %u5c06%u60a3%u8005%u5206%u7fa4%uff0c%u5728%u80a5%u80d6%u60a3%u8005%u4e2d%uff08BMI %u2265 28kg/m2%uff09%uff0c%u4e2d%u8001%u5e74%u60a3%u8005%u7684 C/D %u503c%u663e%u8457%u9ad8%u4e8e%u9752%u5e74%u60a3%u8005%uff08p %uff1c 0.05%uff09%uff1b%u5728%u8d85%u91cd%u60a3%u8005%uff0824kg/m2 %u2264 BMI %uff1c 28kg/m2%uff09%u4e2d%uff0c%u5973%u6027%u9752%u5e74%u60a3%u8005%u7684 C/D %u503c%u663e%u8457%u9ad8%u4e8e%u7537%u6027%u9752%u5e74%u60a3%u8005%uff08p %uff1c 0.05%uff09%u3002ROC %u5206%u6790%u8868%u660e%uff0c%u51cf%u5206%u7387%u8fbe 50% %u65f6%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u4e3a487.8ng/mL%u3002%u60a3%u8005%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u4e0e%u4e0d%u826f%u53cd%u5e94%u7684%u76f8%u5173%u6027%u5206%u6790%u8868%u660e%uff0c%u8840%u836f%u6d53%u5ea6%u9ad8%u4e8e 487.8ng/mL %u7684%u60a3%u8005%u7fa4%u4f53%u4e2d%uff0c%u5747%u672a%u51fa%u73b0%u80be%u529f%u5f02%u5e38%u75c5%u4f8b%uff0c%u4e14%u836f%u7269%u6d53%u5ea6%u548c%u50ac%u4e73%u7d20%u6c34%u5e73%u5347%u9ad8%u3001%u5fc3%u7535%u56fe%u5f02%u5e38%u3001%u809d%u529f%u80fd%u5f02%u5e38%u7b49%u4e0d%u826f%u53cd%u5e94%u65e0%u663e%u8457%u76f8%u5173%u6027%uff08p %uff1e 0.05%uff09%u3002%u7ed3%u8bba%uff1a%u672c%u7814%u7a76%u4e2d%uff0c%u60a3%u8005%u7684%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u666e%u904d%u9ad8%u4e8e%u6307%u5357%u63a8%u8350%u7684%u836f%u7269%u76d1%u6d4b%u6d53%u5ea6%u8303%u56f4%uff0cBMI %u662f%u5176 C/D %u503c%u7684%u91cd%u8981%u5f71%u54cd%u56e0%u7d20%u3002%u5f53%u6cbb%u7597%u6709%u6548%u7387%u8fbe 50% %u65f6%uff0c%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u4e3a 487.8ng/mL %u5e76%u8868%u73b0%u51fa%u826f%u597d%u7684%u5b89%u5168%u6027%uff0c%u4e3a%u5236%u5b9a%u9002%u7528%u4e8e%u4e2d%u56fd%u7cbe%u795e%u5206%u88c2%u75c7%u60a3%u8005%u7684%u6c28%u78fa%u5fc5%u5229%u8840%u836f%u6d53%u5ea6%u76d1%u6d4b%u8303%u56f4%u63d0%u4f9b%u4e86%u91cd%u8981%u53c2%u8003%u3002%u3010%u5173%u952e%u8bcd%u3011%u6c28%u78fa%u5fc5%u5229%uff1b%u8840%u836f%u6d53%u5ea6%uff1bBMI%uff1b%u6cbb%u7597%u53c2%u8003%u8303%u56f4%u3010%u4e2d%u56fe%u5206%u7c7b%u53f7%u3011R969.1 %u3010%u6587%u732e%u6807%u8bc6%u7801%u3011ABlood Concentration Range of Amisulpride in Patients with Schizophrenia: A Study Based on Therapeutic Drug MonitoringTIAN Mi1%uff0c2, DANG Wei1%uff0c2, CHEN Yanming2, DING Jing2, OU Pan2(1.School of Graduate, Xi%u2019an Medical University, Xi%u2019an, Shannxi, 710021;2.Xi%u2019an Mental Health Center, Xi%u2019an, Shannxi, 710000)%u3010Abstract%u3011Objective: Analyze and explore the main influencing factors of blood concentration of amisulpride, establish a reference range for amisulpride treatment drug concentration, and provide reference for individualized medication of Chinese schizophrenia patients.Method: A retrospective collection and analysis were conducted on the TDM results and medication use of 142 hospitalized patients with