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Journal of Rural Medicine ›› 2026, Vol.3 ›› Issue (2) DOI: 10.32629/jrm.v3i2.02111

• 指南解读 • 下一篇

西医及中西医结合治疗晚期肺癌近期疗效的回顾性队列研究

杨小花 , 寇凯鹏 , 王青霞 , 赵丽丽   
  1. 1 . 铜川市人民医院呼吸与危重症医学科
  2. 2 . 铜川市人民医院呼吸与危重症医学科
  3. 3 . 铜川市人民医院呼吸与危重症医学科
  4. 4 . 铜川市人民医院呼吸与危重症医学科
  • 收稿日期:2026-02-01 00:00:00 发布日期:2026-08-13
  • 通讯作者:

  • 作者贡献:
  • 基金资助:
    陕西省自然科学基础研究项目(项目编号:2022JM-563)。

Retrospective Cohort Study on the Short-term Efficacy of Western Medicine and Integrated Traditional Chinese and Western Medicine for Advanced Lung Cancer

YANG Xiaohua KOU Kaipeng WANG Qingxia ZHAO Lili   
  1. Department of Respiratory and Critical Care Medicine, Tongchuan People's Hospital
  2. Department of Respiratory and Critical Care Medicine, Tongchuan People's Hospital
  3. Department of Respiratory and Critical Care Medicine, Tongchuan People's Hospital
  4. Department of Respiratory and Critical Care Medicine, Tongchuan People's Hospital
  • Received:2026-02-01 00:00:00 Online:2026-08-13
  • Contact:

摘要: 目的:评价西医及中西医结合治疗晚期肺癌的近疗期效。 方法:选取 2024-2025 年铜川市人民医院呼吸科收治的 60 例晚期肺癌患者作为研究对象,根据治疗方法不同分为西医组(n=30)和中西医结合组(n=30)。比较两组患者的临床症状改善情况、不良反应发生率,并进行统计学分析。结果:中西医结合组在气短(≤ 1 级占比 53.3%)、乏力(≤ 1 级占比 60.0%)等症状改善方面优于西医组(分别为 33.3%、43.3%),差异有统计学意义(P< 0.05);中西医结合组骨髓抑制发生率(26.7%)、消化系统不良反应发生率(46.7%)均低于西医组(40.0%、63.3%),差异有统计学意义(P < 0.05)。结论:中西医结合治疗晚期肺癌可有效改善临床症状,降低不良反应发生率,为临床治疗优化提供方向。

关键词: 晚期肺癌;回顾性队列研究;中西医结合治疗;西医治疗;近期疗效

Abstract

Objective

To evaluate the short-term efficacy of Western medicine and integrated traditional Chinese and Western medicine in the treatment of advanced lung cancer.

Methods

A total of 60 patients with advanced lung cancer admitted to the Department of Respira- tory Medicine of Tongchuan People's Hospital from 2024 to 2025 were enrolled. They were divided into the Western medicine group (n=30) and the integrated traditional Chinese and Western medicine group ( n=30) according to different treatment regimens. The improvement of clinical symptoms and incidence of adverse reactions were compared between the two groups, and statistical analysis was performed.

Results

The integrated group achieved better improvement in symptoms such as shortness of breath (proportion of grade ≤1: 53.3%) and fatigue (proportion of grade ≤1 60.0%), compared with the Western medicine group (33.3% and 43.3%, respectively), with statistically sig - nificant differences (P<0.05). The incidence of myelosuppression (26.7%) and gastrointestinal adverse reactions (46.7%) in the integrated group was lower than that in the Western medicine group (40.0% and 63.3%), and the differences were statistically significant ( P<0.05).

Conclusion

Integrated traditional Chinese and Western medicine can effectively relieve clinical symptoms and reduce the incidence of ad - verse reactions in patients with advanced lung cancer, which provides a reference for the optimization of clinical treatment.

Key words: Advanced lung cancer; Retrospective cohort study; Integrated traditional Chinese and Western medicine therapy; Western

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